EVALUATION IN VITRO DE L’ACTIVITE ANTHELMINTHIQUE DES PLANTES UTILISEES AU CONGO BRAZZAVILLE DANS LE TRAITEMENT DES MALADIES PARASITAIRES

P. R. ONGOKA, M. DIATEWA, R. AMPA, A. EKOUYA, J. M. OUAMBA, M. GBEASSOR, A. A. ABENA

Résumé


Les extraits de 20 plantes médicinales ont été évalués in vitro pour leur activité anthelminthique. Lombricus terrestri a été utilisé comme modèle animal. Le Levamisol (2, 5 et 10 mg/l) a été utilisé comme substance de référence. Les activités anthelminthiques ont été déterminées aux doses d’extraits aqueux de 5, 10, 15, 20 et 25 mg/l. Les résultats ont été exprimés en termes de temps d’apparition de l’hypermobilité et de temps de  létalité  du  lombric.  L’activité  vermicide  est dose-dépendante pour  19  plantes.  Seule  Heinsia critina a présenté un potentiel vermicide très faible aux doses étudiées.


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Références


Bundy D.A., 1994. Immunoepidemiology of intestinal helminthic infection: The global burden of intestinal nematode disease. Trans Royal Soc Trop Med Hyg; 8: 259-261.

Mali G.R., Mehta A.A., 2008. A review of anthelmintic plants. Natural Product Radiance;

(5): 466-475.

Satyavati G.V., 1990. Use of plant drugs in Indian traditional systems of medicine and their relevance to primary healthcare. In: Farnsworth N.R. and Wagner H. (eds), Economic and medicinal plant research, 4, plant and trditional medicine. London: Academic Press Ltd

Almeida F.A., Garcia K.C.O.D., Torgerson P.R., Amarante A.F.T., 2010. Multiple resistance to anthelmintics by Hoemonchus contortus and Trichostrongylus colubriformis in sheep. Brazil Parasitol Int; 59: 622-625.

Chartier C., Soubirac F., Pors I, Silvestre A., Hubert J., Couquet C., Cabaret J., 2001. Prevalence of anthelmintic resistance in gastro- intestinal nematodes of dairy goats under extensive management conditions in southwestern France. J Helmintol; 75: 325-330.

Kotze C.A., Dobson R.J., Tyrrell K.L., Stein P.A., 2002. High-level ivermectin resistance in a field isolate of Haemonchus contortus associated with a low of resistance in the larval stager: implications resistance detection. Vet Parasitol; 108: 255-263.

Waller P.J., 1997. Anthelmintic resistance.

Veterinary Parasitology ; 72 : 391-405.

Walter P.J., Prichard K.K., 1985.

Chemotherapy of parasitic infections. In : Campbell W.C. and Rew L.S. (eds). New

York: Plenum, pp. 278-539.

Adjanohoun E.E., 1988. Contribution aux études ethnobotaniques et floristiques en République du Congo. Paris : ACCP, 159p.

Bouquet A., 1969. Féticheur et médecine traditionnelle du Congo Brazzaville. Paris : ORSTOM, 282 p.

Ongoka P.R., Abena A.A., Motom M., Ngoliele A., Ekouya A., Diatewa M., Okémy-

Andissa N., Attie R., 2004. Etude

ethnopharmacologique de quelques plantes anthelminthiques du Congo Brazzaville. Rev Méd Pharm. Afr ; 18 : 153-159.

Aron M., Grasse P., 1966. Précis de biologie animale. Paris : Masson et Cie, pp. 878-879.

Grasse P.P., Doumenc D., 1995. Invertébrés, tome 1. Paris : Masson, pp.112-119.

Guissou L.P., Ouedraogo S, Sanfo A., Some N., Lompo M., 1988. Mise au point d’un modèle biologique de test antiparasitaire appliqué aux plantes médecinales. Pharm.

Méd. Trad. Afr. ; 10 : 105-133.

Vidyadhar S., Saidulu M., Gopal T.K., Chamundeeswari D., Umamaheswara Rao, Banji D., 2010. In vitro anthelmintic activity of the whole plant of Enicostemma littorale by using various extracts. International Journal of Applied Biology and Pharmaceutical Technology; I (3): 1119-1125.

Deore S.L., Khadabadi S.S., Kamdi K.S., Ingle V.P., Kawalkar N.G., Sawarkar P.S., Patil U.A., Vyas A.J., 2009. In vitro anthelmintic activity of Cassia tora. Int J Chem Tech Res; 1 (2): 177-179.

Satish B.K., Ravindra A.F., 2009.

Investigation of in vitro anthelmintic activity of Thespesia lampas (Cav.); 2 (2): 69-71.

Ashok Kumar B.S., Lakshman K., Jayaveera K.N., Nandeesh R., Manoj B., Ranganayakulu D., 2010. Comparative in vitro anthelmintic activity of three plants from the Amaranthaceae family. Arch Biol Sci Belgrade; 62 (1): 185-189.

Roy H., Chakraborty A., Bhanja S., Nayak B.S., Mishra S.R., Ellaiah P., 2010. Preliminary phytochemical investigation and anthelmintic activity of Acanthospermum hispidum DC. J Pharm Sci Tech; 2 (5): 217-221.

Yadu Nandan D., Manas Kumar P., 2011.

Evaluation of anthelmintic activity of leaves of Paederia foetida. Int J Pharma Bio Sci; 2 (1): 227-231.

Partap S., Kumar S., Kumar A., Sharma N.K., Jha K.K., 2012. In vitro anthelmintic activity of Luffa cylindrica leaves in Indian adult earthworm. J Pharmacog Phytochem; 1 (2):

-31.

Subach K.R., Jagan Rao N., Binoy Varghese Cheriyan, Muthulakshmi Bhaarati, Sandeep Kumar K., 2012. The anthelmintic activity of Eupatorium triplinerve and Alpinia galanga in Pheritima posthuma and Ascardia galli: A comparative study. Journal of Clinical and Diagnostic Research; 6 (6): 947-950.

Mpiana P.T., Mudogo V., Tshibangu D.S.T., Ngbolua K.N., Shetonde O.M., Mangwala K.P., Mavakala, B.K., 2007. In vitro antisickling activity of anthocyanins extract of a Congolese plant: Alchornea cordifolia M. Arg. J Med Sci; 7 (7): 1182-1186.

Baba Haruna, Onanuga Adebola, 2011.

Preliminary phytochemical screening and antimicrobial evaluation of three medicinal plants used in Nigeria. Afr J Trad Compl Alter Mad; 8 (4): 387-390.

Maitera O.N., Khan M.E., James T.F., 2011.

Phytochemical analysis and the chemotherapeutics of leaves and stem-bark of Nauclea latifolia grown in Hong, Adamawa State Nigeria. Asian J Plant Sci Res; 1 (3): 16-

Apu A.S., Liza M.S., Jamaluddin A.T.M., Md Amran Howlader, Kumer Saha R., Rizwan E., Nasrin N., 2012. Phytochemical screening and in vitro bioactivities of the extracts of aerial part of Boerhavia diffusa Linn. Asian Pac J Trop Biomed; 2 (9): 673-678.

Bate-Smith E.C., 1962. The phenolic constituent of plants and their taxonomic significance, dicotyledons. J Linn Soc Bot; 58:

-103.

Vedha Hari B.N., Saravana Kumar P., Ramya Devi D., 2011. Comparative in vitro anthelmintic activity of the latex of Ficus Religinosa, Ficus elastica and Ficus bengalensis. J Phytol Phytopharm; 3 (3): 26-

Martin R.J., 1997. Mode of action of anthelmintic drugs. Vet J; 154: 11-34.

Thompson D.P., Geary T.G., 1995. The structure and function of helminth surfaces, in Biochemistry and Molecular Biology of parasites, 1st ed, New York: Academic Press, pp.203-2032.


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